How have you impacted someone's life today? At Hackensack
Meridian Health our teams are focused on changing the lives of our
patients by providing the highest level of care each and every day.
From our hospitals, rehab centers and occupational health teams to
our long-term care centers and at-home care capabilities, our
complete spectrum of services will allow you to apply your skills
in multiple settings while building your career, all within New
Jersey's premier healthcare system.
The Postdoc Rsch Fllw, NeuroBio will work under the guidance of
Dr. Vogel studying pediatric neuro-oncology, focusing on patient
samples, translational PDX murine models and 3D organoid models of
rare pediatric central nervous system (CNS) tumors. The research
will seek to understand mechanisms that lead to tumor pathogenesis
and test novel therapeutic approaches. The research carried out in
our lab is closely partnered with patient treatment and the
insights gained from the work will be translated into clinical
approach and treatment strategies for the developing CNS (For
details see Nature Medicine 18, 1797-1804 (2012)). Our lab employs
a number of mouse genetic models with in vivo and in vitro systems
to study tumorigenesis. These include novel subcellular imaging
techniques, molecular/cellular neurobiology, protein biochemistry,
genetic, and pharmacological methods. Our lab has a strong interest
in translational neuroscience research and is focused on developing
novel medical therapies in our models.
A day in the life of Postdoctoral Research Fellow, NeuroBio at
Hackensack Meridian Health includes:
PCR Genotyping mice strains, mouse colony management by setting
up timed breeding for mice pups, and breeders. Orthotopic
implantation of patient derived tumor cells, autopsies,
micro-dissection of brain from embryo and adult mice at varying
stage of neuro-development, collecting fluids, therapeutic
treatment via injections.
Neuronal cell culture and maintenance.
Proficiency in in vitro and in vivo techniques, including,
imaging (bioluminescence, fluorescence, isotopes), histology, PCR,
molecular assays, and other basic laboratory techniques.
Lab maintenance, upkeep with making solutions, reagents, PCR
primers, and ordering equipment.
Perform data analysis and interpretation to interface with
partners in industry to shape clinical approach and translated
treatment to patients
Present results in internal and external research forums such as
Gordon Research Conference, Society for Neuroscience, Society for
Neuro-Oncology. Presentations will be in the format of posters and
talks with expectation of manuscript preparation.
Participate in grant and manuscript writing, as appropriate.
Education, Knowledge, Skills and Abilities Required:
* Hold a Ph.D. or M.D./Ph.D. in neuroscience, genetics,
developmental biology, molecular/cellular biology, regenerative
biology, or biochemistry from an accredited graduate level
institution. * Minimum publication or in preparation of two
articles as first author in a reputable peer-reviewed scientific
journal. * Excellent analytical and presentation skills.
Education, Knowledge, Skills and Abilities Preferred:
* A strong background in biochemical, cellular, neuroscience,
genetic, or developmental biology in mouse models. * Expertise in
cell culture, cell engineering, flow cytometry, rodent handling,
and basic cellular and molecular biology techniques required. *
Show evidence of scientific productivity and writing skills,
documented by authorship in publications.
If you feel that the above description speaks directly to your
strengths and capabilities, then please apply today!